Our Pipeline
Rhythm has developed setmelanotide, a melanocortin-4 receptor (MC4R) agonist that may restore impaired MC4R pathway function caused by genetic variants that occur upstream of the receptor.1
About Rhythm Pharmaceuticals
Transforming the lives of patients and their families living with hyperphagia and severe obesity caused by rare melanocortin-4 receptor pathway diseases
Individuals with variants in genes in the melanocortin-4 receptor (MC4R) pathway or injury to the hypothalamic region may impair pathway activation which can lead to hyperphagia (pathological, insatiable hunger) and severe obesity
Rare Genetic Diseases of Obesity
LEARN MOREHypothalamic Obesity
LEARN MOREReferences
- Collet TH, et al. Mol Metab. 2017;6(10):1321-1329.